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Acetylcholinesterase anticorps
AChE
Reactivité: Humain, Rat, Souris
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Acetylcholinesterase anticorps
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Antigène
Voir toutes Acetylcholinesterase (AChE) Anticorps
Acetylcholinesterase (AChE)
Reactivité
Toutes les réactivités sur Acetylcholinesterase Anticorps
Humain, Rat, Souris
Hôte
Toutes les hôtes sur Acetylcholinesterase Anticorps
Lapin
Clonalité
Toutes les clonalités sur Acetylcholinesterase Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Acetylcholinesterase Anticorps
Cet anticorp Acetylcholinesterase est non-conjugé
Application
Tous les applications à travers Acetylcholinesterase Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody detects endogenous levels of AChE I protein. (region surrounding Lys585)
Réactivité croisée (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Pureté
> 95 % by SDS-PAGE
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Discover our top product AChE Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur Acetylcholinesterase
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Antigène
Acetylcholinesterase (AChE)
Autre désignation
Acetylcholinesterase (AChE Produits )
Synonymes
anticorps ACEE, anticorps ARACHE, anticorps N-ACHE, anticorps YT, anticorps Ache, anticorps GB14873, anticorps zgc:92550, anticorps ACE, anticorps Dsim\\GD20515, anticorps GD20515, anticorps dsim_GLEANR_4292, anticorps ache, anticorps mE1a, anticorps mE1b, anticorps mE1c, anticorps mE1c-long, anticorps mE1d, anticorps mE1d', anticorps mE1e, anticorps arache, anticorps n-ache, anticorps acetylcholinesterase (Cartwright blood group), anticorps acetylcholinesterase 2, anticorps acetylcholinesterase, anticorps Acetylcholine esterase, anticorps acetylcholinesterase (Cartwright blood group) L homeolog, anticorps collagen type I alpha 2 chain, anticorps ACHE, anticorps AChE-2, anticorps Ache, anticorps ache, anticorps Dsim\Ace, anticorps ache.L, anticorps COL1A2, anticorps ACE-1
Sujet
Acetylcholinesterase (AChE) hydrolyzes acetylcholine at synaptic junctions. Alternative mRNA splicing gives rise to three forms of AChE. The T form, also known as the asymmetric form, is soluble and is present in synapses. The H form is also known as the globular form and is present on the outer surfaces of cell membranes. The R form is not known to be a functional species. AChE globular form subunits are GPI-anchored to cell membranes and asymmetric subunits are anchored to basal lamina components by a collagen tail. The catalytic subunits of AChE are oligomers composed of disulfide-linked homodimers. The loss of AChE from cholinergic and noncholinergic neurons in the brain is seen in patients with Alzheimer's disease. However, AChE activity is increased around amyloid plaques, which may be due to a disturbance in calcium homeostasis involving the opening of L-type voltage-dependent calcium channels.Synonyms: AChE, Acetylcholine Esterase, Acetylcholine-Esterase
Poids moléculaire
approx. 70 kDa
ID gène
43
NCBI Accession
NP_000656
UniProt
P22303
Pathways
Skeletal Muscle Fiber Development
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