NCR3 anticorps
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- Antigène Voir toutes NCR3 Anticorps
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NCR3 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This detects endogenous levels of NKp30 protein.
- Réactivité croisée (Details)
- Species reactivity (tested):Human and Rat.
- Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product NCR3 Anticorps primaire
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- Indications d'application
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Autre désignation
- CD337 (NCR3 Produits)
- Synonymes
- anticorps MGC133750, anticorps 1C7, anticorps CD337, anticorps LY117, anticorps MALS, anticorps NKp30, anticorps Nkp30, anticorps natural cytotoxicity triggering receptor 3, anticorps NCR3, anticorps Ncr3
- Sujet
- The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on IL-2 activated NK cells and NK cell lines as well as some in vitro activated γ/δ T cells. NKp30 enhances NK cell triggering and cytolysis of tumor targets and other target cells deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.Synonyms: 1C7, LY117, NCR3, NKp30, Natural cytotoxicity triggering receptor 3
- Poids moléculaire
- approx. 30 kDa
- ID gène
- 259197
- NCBI Accession
- NP_667341
- UniProt
- O14931
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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