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Anoctamin 5 anticorps (C-Term)

ANO5 Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499159
  • Antigène Voir toutes Anoctamin 5 (ANO5) Anticorps
    Anoctamin 5 (ANO5)
    Épitope
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 798-828, C-Term
    Reactivité
    • 15
    • 9
    • 1
    Humain, Souris
    Hôte
    • 16
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Anoctamin 5 est non-conjugé
    Application
    • 16
    • 13
    • 13
    • 7
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    Recognizes ANO5 (C-term).
    Purification
    Protein A Chromatography followed by peptide affinity purification
    Immunogène
    Synthetic peptide -KLH conjugated between 798~828 amino acids from the C-terminal region of Human ANO5. Genename: ANO5
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ANO5 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Anoctamin 5 (ANO5)
    Autre désignation
    ANO5 (ANO5 Produits)
    Synonymes
    anticorps gdd1, anticorps tmem16e, anticorps MGC82557, anticorps TMEM16E, anticorps ano5, anticorps si:dkey-261m9.4, anticorps GDD1, anticorps LGMD2L, anticorps 9330162L24, anticorps Gdd1, anticorps Tmem16e, anticorps anoctamin 5 L homeolog, anticorps anoctamin 5, anticorps anoctamin 5a, anticorps ano5.L, anticorps ANO5, anticorps ano5a, anticorps ano5, anticorps Ano5
    Sujet
    ANO5 is a member of the anoctamin family of transmembrane proteins. This protein is likely a calcium activated chloride channel. Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD), also known as osteogenesis imperfecta with unusual skeletal lesions or gnathodiaphyseal sclerosis. GDD is a rare skeletal syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbone. Patients experience frequent bone fractures caused by trivial accidents in childhood, however the fractures heal normally without bone deformity. The jaw lesions replace the tooth-bearing segments of the maxilla and mandible with fibrous connective tissues, including various amounts of cementum-like calcified mass, sometimes causing facial deformities. Patients also have a propensity for jaw infection and often suffer from purulent osteomyelitis-like symptoms, such as swelling of and pus discharge from the gums, mobility of the teeth, insufficient healing after tooth extraction and exposure of the lesions into the oral cavity.Synonyms: Anoctamin-5, GDD1, Gnathodiaphyseal dysplasia 1 protein, TMEM16E, Transmembrane 16E
    ID gène
    203859
    NCBI Accession
    NP_001136121
    UniProt
    Q75V66
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