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AIFM3 anticorps (N-Term)

AIFM3 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499241
  • Antigène Voir toutes AIFM3 Anticorps
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Épitope
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 14
    • 1
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AIFM3 est non-conjugé
    Application
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to AIFM3.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    AIFM3 antibody was raised against a 16 amino acid peptide from near the amino terminus of human AIFM3.
    Isotype
    IgG
    Top Product
    Discover our top product AIFM3 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: AIFM3 antibody can be used for the detection of AIFM3 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Abstract
    AIFM3 Produits
    Synonymes
    anticorps nfrl-A, anticorps MGC84340, anticorps AIFM3, anticorps LOC100150876, anticorps 2810401C16Rik, anticorps AI840249, anticorps Aifl, anticorps RGD1306028, anticorps AIFL, anticorps apoptosis inducing factor, mitochondria associated 3 L homeolog, anticorps apoptosis inducing factor, mitochondria associated 3, anticorps apoptosis-inducing factor, mitochondrion-associated 3, anticorps aifm3.L, anticorps AIFM3, anticorps aifm3, anticorps Aifm3
    Sujet
    Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.Synonyms: AIFL, Apoptosis-inducing factor 3
    ID gène
    150209
    UniProt
    Q96NN9
    Pathways
    Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
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