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ARL6IP1 anticorps (C-Term)

ARL6IP1 Reactivité: Humain, Souris WB, EIA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499337
  • Antigène Voir toutes ARL6IP1 Anticorps
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    Épitope
    • 14
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 38
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 34
    • 4
    Lapin
    Clonalité
    • 36
    • 2
    Polyclonal
    Conjugué
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARL6IP1 est non-conjugé
    Application
    • 25
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.
    Purification
    Ion exchange chromatography
    Immunogène
    Human ARMER / ARL6IP / AIP1 (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product ARL6IP1 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: ARMER antibody can be used for detection of ARMER at 0.5 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    Autre désignation
    ARL6IP1 (ARL6IP1 Produits)
    Synonymes
    anticorps arl6ip, anticorps MGC56593, anticorps zgc:56593, anticorps zgc:77873, anticorps ARL6IP, anticorps aip1, anticorps armer, anticorps ARL6IP1, anticorps MGC85055, anticorps MGC139614, anticorps DKFZp459O112, anticorps AIP1, anticorps ARMER, anticorps AIP-6, anticorps AL022945, anticorps AU042858, anticorps Aip-1, anticorps Arl6ip, anticorps C85138, anticorps mKIAA0069, anticorps ADP-ribosylation factor-like 6 interacting protein 1, anticorps ADP ribosylation factor like GTPase 6 interacting protein 1, anticorps ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog, anticorps ADP-ribosylation factor like GTPase 6 interacting protein 1, anticorps arl6ip1, anticorps ARL6IP1, anticorps arl6ip1.L, anticorps Arl6ip1
    Sujet
    Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA (1). Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12 (2), other caspases such as caspase-9 are also thought to be activated following ER stress (3). Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, KIAA0069
    ID gène
    23204
    UniProt
    Q15041
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