ATF6 anticorps (N-Term)
-
- Antigène Voir toutes ATF6 Anticorps
- ATF6 (Activating Transcription Factor 6 (ATF6))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp ATF6 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- ATF6 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ATF6. ATF6 has two isoforms (ATF6alpha and ATF6beta), only ATF6alpha is recognized by this antibody.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Human ATF6 (N-Terminus) Peptide
- Isotype
- IgG
- Top Product
- Discover our top product ATF6 Anticorps primaire
-
-
- Indications d'application
-
ELISA. Western Blot: ATF6 antibody can be used for the detection of ATF6 at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
-
- Antigène
- ATF6 (Activating Transcription Factor 6 (ATF6))
- Autre désignation
- ATF6 alpha (ATF6 Produits)
- Synonymes
- anticorps ATF-6-like, anticorps GB16435, anticorps ATF6, anticorps Atf6, anticorps ATF6A, anticorps 9130025P16Rik, anticorps 9630036G24, anticorps AA789574, anticorps Atf6alpha, anticorps ESTM49, anticorps activating transcription factor 6, anticorps uncharacterized LOC412432, anticorps activating transcription factor 6 S homeolog, anticorps cyclic AMP-dependent transcription factor ATF-6 alpha, anticorps ATF6, anticorps LOC412432, anticorps atf6.S, anticorps LOC100122162, anticorps Atf6
- Sujet
- Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus. Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR . ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes (2-4).Synonyms: ATF-6, Activating transcription factor 6 alpha, Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha
- ID gène
- 22926
- NCBI Accession
- NP_031374
- UniProt
- P18850
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
-