Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ANTXR1 anticorps (C-Term)

ANTXR1 Reactivité: Humain, Souris, Rat WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499365
  • Antigène Voir toutes ANTXR1 Anticorps
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Épitope
    • 15
    • 8
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 74
    • 34
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 68
    • 3
    • 3
    Lapin
    Clonalité
    • 71
    • 3
    Polyclonal
    Conjugué
    • 28
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANTXR1 est non-conjugé
    Application
    • 42
    • 29
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    ATR antibody was raised against a peptide corresponding to 13 amino acids near the C-terminus of human ATR. ATR will recognize only the largest isoform.
    Purification
    Ion exchange chromatography
    Immunogène
    Human ATR / TEM8 (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product ANTXR1 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: ATR antibody can be used for detection of ATR by Western blot at 1 to 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Autre désignation
    Anthrax Toxin Receptor 1 (ANTXR1 Produits)
    Synonymes
    anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1
    Sujet
    The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8) (1). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin (2). Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF) (3). This complex is then endocytosed by the cell, acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis (4).Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
    ID gène
    84168
    NCBI Accession
    NP_444262
    UniProt
    Q9H6X2
Vous êtes ici:
Support technique