BCAP31 anticorps (C-Term)

N° du produit ABIN499417

Cet anticorps Lapin Polyclonal détecte spécifiquement BCAP31 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCAP31 anticorps (C-Term) (ABIN499417)

Antigène: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAP31 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-BCAP31 anticorps

Épitope: C-Term

Specificité: BAP31 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human BAP31.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human BAP31 (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot. BAP31 antibody can be used for the detection of BAP31 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur BCAP31

Antigène: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Autre désignation: BCAP31 / BAP31

Sujet: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18 (3,4). It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria (5). Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death (5).Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31

ID gène: 10134

NCBI Accession: NP_005736

UniProt: P51572

Pathways: Positive Regulation of Endopeptidase Activity