BCAP31 anticorps (Intermediate Domain)

N° du produit ABIN499419

Détail du produit anti-BCAP31 anticorps

Antigène: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Épitope: Intermediate Domain

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAP31 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: BAP31 antibody was raised against a 17 amino acid peptide from near the center of human BAP31.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human BAP31 (Intermediate Domain) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: BAP31 antibody can be used for the detection of BAP31 by Western blot at 0.5- 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur BCAP31

Antigène: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Autre désignation: BCAP31 / BAP31 (BCAP31 Produits)

Synonymes: anticorps 6c6-ag, anticorps bap31, anticorps cdm, anticorps dxs1357e, anticorps BCAP31, anticorps Bap31, anticorps 6C6-AG, anticorps BAP31, anticorps CDM, anticorps DXS1357E, anticorps CALD1, anticorps caldesmon, anticorps si:bz30i22.4, anticorps si:rp71-30i22.4, anticorps zgc:56389, anticorps B-cell receptor associated protein 31, anticorps receptor-associated protein, anticorps lipopeptide mating pheromone precursor bap3-1, anticorps B cell receptor associated protein 31, anticorps B-cell receptor-associated protein 31, anticorps B-cell receptor associated protein 31 L homeolog, anticorps bcap31, anticorps BAP31, anticorps bap3-1, anticorps BCAP31, anticorps Bcap31, anticorps bcap31.L

Sujet: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18 (3,4). Bap31 may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria (5). Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopically, is also a potent inducer cell death (5).Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31

ID gène: 10134

NCBI Accession: NP_005736

UniProt: P51572

Pathways: Positive Regulation of Endopeptidase Activity