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BFAR anticorps (C-Term)

BFAR Reactivité: Humain, Souris, Rat WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499449
  • Antigène Voir toutes BFAR Anticorps
    BFAR (Bifunctional Apoptosis Regulator (BFAR))
    Épitope
    • 14
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 28
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 35
    • 1
    Lapin
    Clonalité
    • 35
    • 1
    Polyclonal
    Conjugué
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BFAR est non-conjugé
    Application
    • 24
    • 23
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    BFAR antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BFAR.
    Isotype
    IgG
    Top Product
    Discover our top product BFAR Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: BFAR antibody can be used for detection of BFAR at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    BFAR (Bifunctional Apoptosis Regulator (BFAR))
    Autre désignation
    BFAR / RNF47 (BFAR Produits)
    Synonymes
    anticorps BFAR, anticorps MGC137916, anticorps bfar, anticorps BAR, anticorps RNF47, anticorps 3010001A07Rik, anticorps AI666707, anticorps AW107665, anticorps Bar, anticorps Rnf47, anticorps bifunctional apoptosis regulator, anticorps bifunctional apoptosis regulator L homeolog, anticorps BFAR, anticorps bfar.L, anticorps bfar, anticorps Bfar
    Sujet
    The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.Synonyms: BAR, Bifunctional apoptosis regulator, RING finger protein 47
    ID gène
    51283
    NCBI Accession
    NP_057645
    UniProt
    Q9NZS9
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