BICD1 anticorps (C-Term)

N° du produit ABIN499455

Détail du produit anti-BICD1 anticorps

Antigène: BICD1 (Bicaudal D Homolog 1 (BICD1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BICD1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to BICD1. This antibody will only recognize the larger isoform.

Purification: Affinity chromatography purified via peptide column

Immunogène: BICD1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BICD1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: BICD1 antibody can be used for detection of BICD1 at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur BICD1

Antigène: BICD1 (Bicaudal D Homolog 1 (BICD1))

Autre désignation: BICD1 (BICD1 Produits)

Synonymes: anticorps BICD, anticorps B830009D06Rik, anticorps mKIAA4125, anticorps bicaudal D homolog 1 L homeolog, anticorps BICD cargo adaptor 1, anticorps bicaudal D homolog 1 (Drosophila), anticorps bicd1.L, anticorps BICD1, anticorps Bicd1

Sujet: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. At least two isoforms of BICD1 are known to exist.Synonyms: Bic-D1, Protein bicaudal D homolog 1

ID gène: 636

NCBI Accession: NP_001705

UniProt: Q96G01

Pathways: Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location