SH3GLB1 anticorps (C-Term)

N° du produit ABIN499465

Détail du produit anti-SH3GLB1 anticorps

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3GLB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This anitbody reacts to BIF.

Purification: Affinity chromatography purified via peptide column

Immunogène: BIF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BIF.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western BLot: BIF antibody can be used for the detection of BIF at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SH3GLB1

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Autre désignation: Endophilin-B1 (SH3GLB1 Produits)

Synonymes: anticorps im:5777505, anticorps wu:fa08f03, anticorps wu:fb13e12, anticorps MGC79086, anticorps sh3glb1, anticorps wu:fc55h11, anticorps wu:fj98d09, anticorps AA409932, anticorps AI314629, anticorps AU015566, anticorps Bif-1, anticorps mKIAA0491, anticorps PPP1R70, anticorps dJ612B15.2, anticorps SH3-domain GRB2-like endophilin B1b, anticorps SH3 domain GRB2 like, endophilin B1 S homeolog, anticorps SH3 domain GRB2 like, endophilin B1, anticorps SH3 domain containing GRB2 like, endophilin B1, anticorps SH3-domain GRB2-like endophilin B1a, anticorps SH3-domain GRB2-like B1 (endophilin), anticorps SH3 domain -containing GRB2-like endophilin B1, anticorps SH3 domain containing GRB2 like endophilin B1, anticorps sh3glb1b, anticorps sh3glb1.S, anticorps sh3glb1, anticorps SH3GLB1, anticorps sh3glb1a, anticorps Sh3glb1

Sujet: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes. Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF), a member of the endophilin B family that is associated with intracellular membranes.. Following this interaction, Bax undergoes a conformational change and translocates to mitochondrial membranes. The Bax/BIF interaction appears to be enhanced by apoptotic stimuli, suggesting that BIF acts as the trigger to activate Bax, and as suppression of BIF promoted HeLa cell colony formation in soft agar, it may have a role in the suppression of cancer progression. At least two isoforms of BIF are known to exist.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1

ID gène: 51100

UniProt: Q9Y371

Pathways: Autophagy