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BRSK1 anticorps (C-Term)

BRSK1 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499499
  • Antigène Voir toutes BRSK1 Anticorps
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    Épitope
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 51
    • 31
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 73
    Lapin
    Clonalité
    • 72
    • 1
    Polyclonal
    Conjugué
    • 21
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BRSK1 est non-conjugé
    Application
    • 47
    • 38
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to BRSK1.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    BRSK1 antibody was raised against a 28 amino acid peptide from near the carboxy terminus of human BRSK1.
    Isotype
    IgG
    Top Product
    Discover our top product BRSK1 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: BRSK1 antibody can be used for detection of BRSK1 at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    Autre désignation
    BRSK1 (BRSK1 Produits)
    Synonymes
    anticorps BRSK1, anticorps hSAD1, anticorps Gm1100, anticorps SAD-B, anticorps SADB, anticorps RGD1563268, anticorps Sad-b, anticorps BR serine/threonine kinase 1, anticorps BRSK1, anticorps Brsk1
    Sujet
    BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.Synonyms: BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B
    ID gène
    84446
    UniProt
    Q8TDC3
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