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CALHM1 anticorps (N-Term)

CALHM1 Reactivité: Humain, Rat, Souris WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499519
  • Antigène Voir toutes CALHM1 Anticorps
    CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
    Épitope
    • 15
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 23
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CALHM1 est non-conjugé
    Application
    • 21
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    17 amino acid peptide near the amino terminus of Human CALHM1
    Isotype
    IgG
  • Indications d'application
    ELISA. Western Blot: CALHM1 antibody can be used for detection of CALHM1 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
    Autre désignation
    CALHM1 / FAM26C (CALHM1 Produits)
    Synonymes
    anticorps FAM26C, anticorps Fam26c, anticorps RGD1564891, anticorps EG546729, anticorps calcium homeostasis modulator 1, anticorps novel protein similar to vertebrate calcium homeostasis modulator protein family, anticorps CALHM1, anticorps LOC557535, anticorps Calhm1
    Sujet
    Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-b (Ab) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Ab levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.Synonyms: Calcium homeostasis modulator protein 1
    ID gène
    255022
    NCBI Accession
    NP_001001412
    UniProt
    Q8IU99
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