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5-Methylcytosine anticorps (AbBy Fluor® 750)

WB, FACS, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 750
N° du produit ABIN4995770
  • Antigène
    5-Methylcytosine
    Reactivité
    Veuillez nous consulter SVP
    Hôte
    • 21
    • 9
    • 3
    Lapin
    Clonalité
    • 23
    • 10
    Polyclonal
    Conjugué
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 750
    Application
    • 19
    • 15
    • 12
    • 10
    • 9
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Réactivité croisée (Details)
    5 MethylCytosine
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated 5 MethylCytosine
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    5-Methylcytosine
    Autre désignation
    5 MethylCytosine
    Classe de substances
    Chemical
    Sujet

    Synonyms: 5-Methyl Cytidine, 5 m C, 5 mC, 5 me C, 5 Me Cytidine, 5 MeCyd, 5 Methyl Cytidine, 5 MethylCytosine, 5-mC, 5-Me Cytidine, 5-Methyl-Cytosine, 5-MethylCytidine.

    Background: Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.

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