CCR3 anticorps (C-Term)
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- Antigène Voir toutes CCR3 Anticorps
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCR3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- CCR3 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human CCR3.
- Purification
- Immunoaffinity
- Immunogène
- Human CCR3 (C-Terminus) Peptide
- Isotype
- IgG
- Top Product
- Discover our top product CCR3 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: CCR3 antibody can be used for the detection of CCR3 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Autre désignation
- CD193 / CCR3 (CCR3 Produits)
- Synonymes
- anticorps CC-CKR-3, anticorps CD193, anticorps CKR3, anticorps CMKBR3, anticorps CC-CKR3, anticorps Cmkbr1l2, anticorps Cmkbr3, anticorps C-C motif chemokine receptor 3, anticorps chemokine (C-C motif) receptor 3, anticorps CCR3, anticorps Ccr3
- Sujet
- Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS (3,4). High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor
- ID gène
- 1232
- NCBI Accession
- NP_847899
- UniProt
- P51677
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