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BIRC2 anticorps (C-Term)

BIRC2 Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499623
  • Antigène Voir toutes BIRC2 Anticorps
    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
    Épitope
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 33
    • 4
    • 4
    Humain, Souris
    Hôte
    • 29
    • 4
    Lapin
    Clonalité
    • 28
    • 5
    Polyclonal
    Conjugué
    • 18
    • 6
    • 5
    • 2
    • 1
    • 1
    Cet anticorp BIRC2 est non-conjugé
    Application
    • 29
    • 18
    • 17
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    C-IAP antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 c-IAP antibody detects both c-IAP1 and c-IAP2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Human cIAP (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product BIRC2 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: cIAP antibody can be used for the detection of c-IAP at 1 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
    Autre désignation
    IAP2 / BIRC2 (BIRC2 Produits)
    Sujet
    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases (1 for review). The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspasesSynonyms: API1, Baculoviral IAP repeat-containing protein 2, C-IAP1, HIAP-2, HIAP2, IAP homolog B, Inhibitor of apoptosis protein 2, MIHB, RING finger protein 48, RNF48, TNFR2-TRAF-signaling complex protein 2, cIAP1
    ID gène
    329
    NCBI Accession
    NP_001157
    UniProt
    Q13490
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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