C1QTNF4
Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA. Western Blot: CTRP4 antibody can be used for the detection of CTRP4 at 1 - 2 μg/mL. Ratbrain cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Antigène
C1QTNF4
(Complement C1q Tumor Necrosis Factor-Related Protein 4 (C1QTNF4))
anticorps c1qt4, anticorps CTRP4, anticorps ZACRP4, anticorps 0710001E10Rik, anticorps 9430004J15Rik, anticorps zgc:112213, anticorps C1q and TNF related 4, anticorps C1q and tumor necrosis factor related protein 4, anticorps C1q and TNF related 4 S homeolog, anticorps c1qtnf4, anticorps C1QTNF4, anticorps C1qtnf4, anticorps c1qtnf4.S
Sujet
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of mouse CTRP4 have been reported.Synonyms: CTRP4, Complement C1q tumor necrosis factor-related protein 4