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CUEDC2 anticorps (C-Term)

CUEDC2 Reactivité: Humain, Souris, Rat WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499688
  • Antigène Voir toutes CUEDC2 Anticorps
    CUEDC2 (CUE Domain Containing 2 (CUEDC2))
    Épitope
    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 35
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 48
    • 2
    Lapin
    Clonalité
    • 48
    • 2
    Polyclonal
    Conjugué
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CUEDC2 est non-conjugé
    Application
    • 37
    • 14
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to CUEDC2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    CUEDC2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CUEDC2.
    Isotype
    IgG
    Top Product
    Discover our top product CUEDC2 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: CUEDC2 antibody can be used for detection of CUEDC2 at 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    CUEDC2 (CUE Domain Containing 2 (CUEDC2))
    Autre désignation
    CUEDC2 (CUEDC2 Produits)
    Synonymes
    anticorps cuedc2, anticorps MGC81368, anticorps C10orf66, anticorps bA18I14.5, anticorps 3010002G01Rik, anticorps wu:fi42e02, anticorps zgc:92255, anticorps CUE domain containing 2 S homeolog, anticorps CUE domain containing 2, anticorps CUE domain containing 2 L homeolog, anticorps cuedc2.S, anticorps CUEDC2, anticorps cuedc2.L, anticorps cuedc2, anticorps Cuedc2
    Sujet
    The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-a and IKK-b and decrease the activation of NF-kB by decreasing the activation of IKK. CUEDC2 antibody will not cross-react with CUEDC1.Synonyms: C10orf66, CUE domain-containing protein 2, HOYS6
    ID gène
    79004
    NCBI Accession
    NP_076945
    UniProt
    Q9H467
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