CUEDC2 anticorps (C-Term)

N° du produit ABIN499688

Détail du produit anti-CUEDC2 anticorps

Antigène: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CUEDC2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CUEDC2.

Purification: Affinity chromatography purified via peptide column

Immunogène: CUEDC2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CUEDC2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CUEDC2 antibody can be used for detection of CUEDC2 at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CUEDC2

Antigène: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Autre désignation: CUEDC2 (CUEDC2 Produits)

Synonymes: anticorps cuedc2, anticorps MGC81368, anticorps C10orf66, anticorps bA18I14.5, anticorps 3010002G01Rik, anticorps wu:fi42e02, anticorps zgc:92255, anticorps CUE domain containing 2 S homeolog, anticorps CUE domain containing 2, anticorps CUE domain containing 2 L homeolog, anticorps cuedc2.S, anticorps CUEDC2, anticorps cuedc2.L, anticorps cuedc2, anticorps Cuedc2

Sujet: The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-a and IKK-b and decrease the activation of NF-kB by decreasing the activation of IKK. CUEDC2 antibody will not cross-react with CUEDC1.Synonyms: C10orf66, CUE domain-containing protein 2, HOYS6

ID gène: 79004

NCBI Accession: NP_076945

UniProt: Q9H467