ZFHX3 anticorps (AA 301-400) (AbBy Fluor® 750)
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- Antigène Voir toutes ZFHX3 Anticorps
- ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
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Épitope
- AA 301-400
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZFHX3 est conjugé à/à la AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ATBF1
- Isotype
- IgG
- Top Product
- Discover our top product ZFHX3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
- Autre désignation
- ATBF1 (ZFHX3 Produits)
- Synonymes
- anticorps ZFHX3, anticorps ATBF1, anticorps ATBT, anticorps ZNF927, anticorps A230102L03Rik, anticorps Atbf1, anticorps WBP9, anticorps mKIAA4228, anticorps RGD1560268, anticorps zax-2, anticorps zinc finger homeobox 3, anticorps AT-binding transcription factor1, anticorps zfhx3, anticorps ZFHX3, anticorps ATBF1/ZFHX4b, anticorps Zfhx3
- Sujet
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Synonyms: Alpha fetoprotein enhancer binding protein, AT binding transcription factor 1, AT mot binding factor, ATBT, ZFHX3, ZFHX3_HUMAN.
Background: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (13). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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