TTC8 anticorps (AA 251-330) (AbBy Fluor® 750)

N° du produit ABIN4997231

Détail du produit anti-TTC8 anticorps (AbBy Fluor® 750)

Antigène: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Épitope: AA 251-330

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTC8 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BBS8

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TTC8

Antigène: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Autre désignation: BBS8/TTC8 (TTC8 Produits)

Synonymes: anticorps TTC8, anticorps bbs8, anticorps fk26c02, anticorps wu:fk26c02, anticorps zgc:136718, anticorps DKFZp459L2429, anticorps BBS8, anticorps RP51, anticorps 0610012F22Rik, anticorps AV001447, anticorps tetratricopeptide repeat domain 8, anticorps TTC8, anticorps ttc8, anticorps lpa_01174, anticorps Ttc8

Sujet:

Synonyms: Bardet Biedl syndrome 8 protein, Bardet Biedl syndrome type 8, Bardet-Biedl syndrome 8 protein, BBS8, Tetratricopeptide repeat domain 8, Tetratricopeptide repeat protein 8, TPR repeat protein 8, TTC 8, Ttc8, TTC8_HUMAN.

Background: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. BBS patients also have an increased risk of developing diabetes, hypertension, and congenital heart defects. BBS is a heterogeneous disorder mapping to eight genetic loci and encoding eight proteins, BBS1-BBS8. Five BBS proteins encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS2 contains two overlapping genes: BBS2L1 and BBS2L2. BBSL1 was re-named BBS7, whereas BBS2L2 independently funcitons as BBS1. BBS7 contains 672 amino acids and is expressed at low to moderate levels in most human tissues.

Pathways: Signalisation Hedgehog