BCL6B anticorps (AA 141-440) (AbBy Fluor® 750)
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- Antigène Voir toutes BCL6B Anticorps
- BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
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Épitope
- AA 141-440
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BCL6B est conjugé à/à la AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human BCL6B
- Isotype
- IgG
- Top Product
- Discover our top product BCL6B Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
- Autre désignation
- BCL6B (BCL6B Produits)
- Synonymes
- anticorps BAZF, anticorps ZBTB28, anticorps ZNF62, anticorps Bazf, anticorps RGD1563179, anticorps B-cell CLL/lymphoma 6B, anticorps B cell CLL/lymphoma 6, member B, anticorps B-cell CLL/lymphoma 6, member B, anticorps BCL6B, anticorps Bcl6b, anticorps bcl6b
- Sujet
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Synonyms: B cell CLL/lymphoma 6, member B zinc finger protein, B-cell CLL/lymphoma 6, member B zinc finger protein, BAZF, Bcl6 associated zinc finger protein, Bcl6-associated zinc finger protein, ZBTB28, Zinc finger protein 62, ZNF62.
Background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.
- Pathways
- BCR Signaling
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