RYBP anticorps
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- Antigène Voir toutes RYBP Anticorps
- RYBP (RING1 and YY1 Binding Protein (RYBP))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RYBP est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- DEDAF antibody was raised against a synthetic peptide corresponding to amino acids 215 to 228 of human DEDAF. The sequence is identical to that of mouse origin.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Human DEDAF Peptide
- Isotype
- IgG
- Top Product
- Discover our top product RYBP Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: 0.5 to 1 μg/mL. A band at approximately 32 kDa can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- RYBP (RING1 and YY1 Binding Protein (RYBP))
- Autre désignation
- RYBP (RYBP Produits)
- Synonymes
- anticorps AAP1, anticorps DEDAF, anticorps YEAF1, anticorps 2410018J24Rik, anticorps rybp, anticorps aap1, anticorps dedaf, anticorps yeaf1, anticorps cb337, anticorps wu:fi34f03, anticorps Dedaf, anticorps zgc:153842, anticorps RING1 and YY1 binding protein, anticorps RING1 and YY1 binding protein L homeolog, anticorps RING1 and YY1 binding protein a, anticorps RING1 and YY1 binding protein b, anticorps RYBP, anticorps Rybp, anticorps rybp, anticorps rybp.L, anticorps rybpa, anticorps rybpb
- Sujet
- Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor . DEDAF is identical to the transcriptional repressor RYBP (2). DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.Synonyms: AAP-1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Death effector domain-associated factor, RING1 and YY1-binding protein, YEAF1, YY1 and E4TF1-associated factor 1
- ID gène
- 23429
- UniProt
- Q8N488
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