STK17A anticorps (N-Term)

N° du produit ABIN499768

Détail du produit anti-STK17A anticorps

Antigène: STK17A (serine/threonine Kinase 17a (STK17A))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK17A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. DRAK1 antibody has no cross responses to DRAK2, DAP or ZIP kinases.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human DRAK1 (N-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 - 1 μg/mL. A431 or MOLT4 whole cell lysate can be used as positivecontrol and an approximately 50 kDa band can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur STK17A

Antigène: STK17A (serine/threonine Kinase 17a (STK17A))

Autre désignation: STK17A / DRAK1 (STK17A Produits)

Synonymes: anticorps STK17A, anticorps DRAK1, anticorps RDRAK1, anticorps serine/threonine kinase 17a, anticorps serine/threonine kinase 17a L homeolog, anticorps STK17A, anticorps stk17a, anticorps stk17a.L

Sujet: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).Synonyms: DAP kinase-related apoptosis-inducing protein kinase 1, Serine/threonine-protein kinase 17A

ID gène: 9263

UniProt: Q9UEE5