EFHD2 anticorps (N-Term)

N° du produit ABIN499784

Détail du produit anti-EFHD2 anticorps

Antigène: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFHD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: EFHD2 antibody was raised against a 16 amino acid peptide near the amino terminus of human EFHD2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur EFHD2

Antigène: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Autre désignation: EFHD2 (EFHD2 Produits)

Synonymes: anticorps SWS1, anticorps efhd2, anticorps EFHD2, anticorps MGC131292, anticorps 2600015J22Rik, anticorps AA408606, anticorps D4Wsu27e, anticorps si:dkey-72l14.9, anticorps wu:fb80e07, anticorps EF-hand domain family member D2, anticorps EF-hand domain family, member D2, anticorps EF-hand domain family member D2 L homeolog, anticorps EF hand domain containing 2, anticorps EFHD2, anticorps Efhd2, anticorps efhd2, anticorps efhd2.L

Sujet: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.Synonyms: EF-hand domain-containing protein D2, SWS1, Swiprosin 1, Swiprosin-1

ID gène: 79180

NCBI Accession: NP_077305

UniProt: Q96C19