ESX Homeobox 1 anticorps (Center)

N° du produit ABIN499804

Détail du produit anti-ESX Homeobox 1 anticorps

Antigène: ESX Homeobox 1 (ESX1)

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESX Homeobox 1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: ESX1 antibody was raised against a 19 amino acid peptide near the center of human ESX1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ESX Homeobox 1

Antigène: ESX Homeobox 1 (ESX1)

Autre désignation: ESX1 (ESX1 Produits)

Synonymes: anticorps ESX1L, anticorps ESXR1, anticorps Spx1, anticorps ESX homeobox 1, anticorps extraembryonic, spermatogenesis, homeobox 1, anticorps ESX1, anticorps Esx1

Sujet: Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.Synonyms: ESX1L, ESX1R, Homeobox protein ESX1

ID gène: 80712

UniProt: Q8N693