TMC6 anticorps (N-Term)

N° du produit ABIN499806

Détail du produit anti-TMC6 anticorps

Antigène: TMC6 (Transmembrane Channel-Like 6 (TMC6))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to EVER1.

Purification: Affinity chromatography purified via peptide column

Immunogène: EVER1 antibody was raised against a 14 amino acid peptide from near the amino terminus of human EVER1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TMC6

Antigène: TMC6 (Transmembrane Channel-Like 6 (TMC6))

Autre désignation: TMC6 / EVER1 (TMC6 Produits)

Synonymes: anticorps EVER1, anticorps zgc:92610, anticorps MGC83549, anticorps ever1, anticorps EV1, anticorps EVIN1, anticorps LAK-4P, anticorps D11Ertd204e, anticorps transmembrane channel like 6, anticorps transmembrane channel-like 6b, anticorps transmembrane channel like 6 L homeolog, anticorps transmembrane channel-like gene family 6, anticorps TMC6, anticorps tmc6b, anticorps tmc6.L, anticorps tmc6, anticorps Tmc6

Sujet: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance. At least four isoforms of EVER1 are known to exist. This EVER1 antibody does not cross-react with EVER2.Synonyms: EVIN1, Epidermodysplasia verruciformis protein 1, LAK-4, Transmembrane channel-like protein 6

ID gène: 11322

UniProt: Q7Z403