FKBP15 anticorps (N-Term)

N° du produit ABIN499840

Détail du produit anti-FKBP15 anticorps

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to FKBP15.

Purification: Affinity chromatography purified via peptide column

Immunogène: FKBP15 antibody was raised against a 15 amino acid peptide from near the amino terminus of human FKBP15.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur FKBP15

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Autre désignation: FKBP15 (FKBP15 Produits)

Synonymes: anticorps KIAA0674, anticorps DKFZp469F024, anticorps BB131447, anticorps C430014M02Rik, anticorps FKBO133, anticorps FKBP-133, anticorps FKBP-15, anticorps FKBP133, anticorps mKIAA0674, anticorps RGD1304816, anticorps PPP1R76, anticorps FK506 binding protein 15, anticorps si:ch211-208h16.4, anticorps FKBP15, anticorps si:ch211-208h16.4, anticorps Fkbp15

Sujet: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.Synonyms: 133 kDa FK506-binding protein, FK506-binding protein 15, FKBP133, KIAA0674, WAFL, WASP and FKBP-like

ID gène: 23307

NCBI Accession: NP_056073

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interactome