CAF1p55 anticorps (AbBy Fluor® 680)
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- Antigène Tous les produits CAF1p55 (CAF1)
- CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CAF1p55 est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CAF1p55
- Isotype
- IgG
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))
- Autre désignation
- CAF1p55 (CAF1 Produits)
- Sujet
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Synonyms: Caf 1, CAF-1, CAF-1 P55 subunit, CAF1 p55 subunit, CAF1A, CAF1P55, chaf1b, Chromatin assembly factor 1 p55 subunit, Chromatin assembly factor 1 p60 subunit, chromatin assembly factor 1 subunit, Chromatin assembly factor I, dCAF-1, dCAF1, Human chromatin assembly factor-I p55 subunit, Nucleosome remodeling factor 55 kDa subunit, NURF 55, NURF-55, p55, Probable histone binding protein Caf1, VPRBP_HUMAN.
Background: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
- ID gène
- 9730
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