GOLPH3 anticorps (N-Term)
-
- Antigène Voir toutes GOLPH3 Anticorps
- GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GOLPH3 est non-conjugé
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- GOLPH3 antibody was raised against a 14 amino acid peptide from near the amino terminus of human GOLPH3.
- Isotype
- IgG
- Top Product
- Discover our top product GOLPH3 Anticorps primaire
-
-
- Indications d'application
-
ELISA. Western Blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
-
- Antigène
- GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))
- Autre désignation
- Golgi Phosphoprotein 3 / GOLPH3 (GOLPH3 Produits)
- Synonymes
- anticorps wu:fj66a10, anticorps zgc:101573, anticorps zgc:110223, anticorps 4733401N08Rik, anticorps 5730410D03Rik, anticorps AW413496, anticorps GOPP1, anticorps GPP34, anticorps MIDAS, anticorps Gmx33, anticorps golgi phosphoprotein 3, anticorps golph3, anticorps CpipJ_CPIJ009278, anticorps Golph3, anticorps GOLPH3
- Sujet
- GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.Synonyms: Coat protein GPP34, GPP34, MIDAS, Mitochondrial DNA absence factor
- ID gène
- 64083
- UniProt
- Q9H4A6
-