CASC3 anticorps (AA 501-600) (AbBy Fluor® 680)
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- Antigène Voir toutes CASC3 Anticorps
- CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
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Épitope
- AA 501-600
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CASC3 est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Cow,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CASC3/MLN51
- Isotype
- IgG
- Top Product
- Discover our top product CASC3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
- Autre désignation
- CASC3 (CASC3 Produits)
- Synonymes
- anticorps BTZ, anticorps MLN51, anticorps Btz, anticorps Mln51, anticorps CASC3, anticorps btz, anticorps mln51, anticorps StMLN51, anticorps barentsz, anticorps XlMLN51, anticorps cancer susceptibility 3, anticorps cancer susceptibility candidate 3, anticorps protein CASC3, anticorps cancer susceptibility 3 S homeolog, anticorps CASC3, anticorps Casc3, anticorps casc3, anticorps casc3.S
- Sujet
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Synonyms: Barentsz protein, Btz, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node protein 51, MLN 51 protein, MLN51, Protein barentsz, Protein CASC3, Protein MLN 51, MLN51, CASC3_HUMAN.
Background: The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonexon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.
- ID gène
- 22794
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