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CBLN2 anticorps (AA 151-224) (AbBy Fluor® 750)

CBLN2 Reactivité: Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 750
N° du produit ABIN4999169
  • Antigène Tous les produits CBLN2
    CBLN2 (Cerebellin 2 Precursor (CBLN2))
    Épitope
    • 14
    • 11
    • 8
    • 7
    • 1
    • 1
    • 1
    AA 151-224
    Reactivité
    • 28
    • 25
    • 20
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 42
    Lapin
    Clonalité
    • 42
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CBLN2 est conjugé à/à la AbBy Fluor® 750
    Application
    • 35
    • 20
    • 13
    • 12
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CBLN2
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CBLN2 (Cerebellin 2 Precursor (CBLN2))
    Autre désignation
    CBLN2 (CBLN2 Produits)
    Synonymes
    anticorps MGC64397, anticorps si:dkey-82k12.11, anticorps 6330593N19Rik, anticorps A730004O05, anticorps zgc:163051, anticorps cerebellin 2 precursor, anticorps cerebellin 2 precursor L homeolog, anticorps cerebellin 2a precursor, anticorps cerebellin 2 precursor protein, anticorps cerebellin 2b precursor, anticorps CBLN2, anticorps cbln2.L, anticorps cbln2, anticorps cbln2a, anticorps Cbln2, anticorps cbln2b
    Sujet

    Synonyms: A730004O05, Cbln2, CBLN2_HUMAN, Cerebellin 2, Cerebellin 2 precursor, Cerebellin-2, OTTHUMP00000163726.

    Background: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other?s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.

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