GRIK1 anticorps (Center)

N° du produit ABIN499922

Détail du produit anti-GRIK1 anticorps

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: Grik1 antibody was raised against a 16 amino acid peptide near the center of the human Grik1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GRIK1

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Autre désignation: Glutamate Receptor 5 / GLUR5 (GRIK1 Produits)

Synonymes: anticorps GRIK1, anticorps grik1, anticorps fv36b03, anticorps wu:fv36b03, anticorps EAA3, anticorps EEA3, anticorps GLR5, anticorps GLUR5, anticorps GluK1, anticorps A830007B11Rik, anticorps D16Ium24, anticorps D16Ium24e, anticorps GluK5, anticorps Glur-5, anticorps Glur5, anticorps Glurbeta1, anticorps GluR5, anticorps glutamate ionotropic receptor kainate type subunit 1, anticorps glutamate receptor, ionotropic, kainate 1a, anticorps glutamate receptor, ionotropic, kainate 1, anticorps GRIK1, anticorps grik1a, anticorps Grik1

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.Synonyms: EAA3, Excitatory amino acid receptor 3, GRIK1, Glutamate receptor ionotropic kainate 1

ID gène: 2897

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity