HINT1 anticorps (Center)

N° du produit ABIN499948

Détail du produit anti-HINT1 anticorps

Antigène: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HINT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to HINT1.

Purification: Affinity chromatography purified via peptide column

Immunogène: HINT1 antibody was raised against a 17 amino acid peptide near the center of the human HINT1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur HINT1

Antigène: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Autre désignation: HINT1 (HINT1 Produits)

Synonymes: anticorps hint, anticorps pkci-1, anticorps prkcnh1, anticorps HINT, anticorps NMAN, anticorps PKCI-1, anticorps PRKCNH1, anticorps AA673479, anticorps Hint, anticorps Ipk1, anticorps Pkci, anticorps Prkci, anticorps zgc:103764, anticorps CHPKCI, anticorps HINTZ, anticorps PKCIZ, anticorps histidine triad nucleotide binding protein 1, anticorps histidine triad nucleotide binding protein 1 S homeolog, anticorps histidine triad nucleotide binding protein 1-Z, anticorps Histidine triad nucleotide-binding protein 1, anticorps HINT1, anticorps hint1, anticorps Hint1, anticorps hint1.S, anticorps HINT1Z, anticorps hint-1

Sujet: Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.Synonyms: Adenosine 5'-monophosphoramidase, HINT, HINT1, Histidine triad nucleotide-binding protein 1, PKCI-1, PKCI1, PRKCNH1, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1

ID gène: 3094

NCBI Accession: NP_005331

UniProt: P49773