CDC14A anticorps (AA 51-150) (AbBy Fluor® 680)
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- Antigène Voir toutes CDC14A Anticorps
- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
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Épitope
- AA 51-150
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDC14A est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Cdc14A
- Isotype
- IgG
- Top Product
- Discover our top product CDC14A Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
- Autre désignation
- Cdc14A (CDC14A Produits)
- Synonymes
- anticorps cdc14, anticorps hCDC14, anticorps xcdc14a, anticorps A830059A17Rik, anticorps CDC14A2, anticorps CDC14a1, anticorps Cdc14, anticorps CDC14A, anticorps zgc:63654, anticorps cell division cycle 14A, anticorps Dual specificity protein phosphatase CDC14A, anticorps dual specificity protein phosphatase CDC14A, anticorps cell division cycle 14A L homeolog, anticorps CDC14 cell division cycle 14A, anticorps cell division cycle 14Aa, anticorps CDC14A, anticorps TVAG_168700, anticorps TVAG_479730, anticorps TVAG_362610, anticorps TVAG_490830, anticorps GL50803_9270, anticorps CMU_014610, anticorps cdc14a.L, anticorps Cdc14a, anticorps cdc14a, anticorps cdc14aa
- Sujet
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Synonyms: CDC 10, Cdc 14, Cdc 14A, Cdc 14A1, Cdc 14A2, CDC10, Cdc14, CDC14 cell division cycle 14 homolog A, CDC14 homolog A, Cdc14A1, Cdc14A2, Cell division cycle 14 homolog A, Dual specicity protein phosphatase CDC 14A, Dual specicity protein phosphatase CDC14A, hCDC14, CC14A_HUMAN.
Background: In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells. Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation.
- ID gène
- 8556
- UniProt
- Q9UNH5
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