CDH18 anticorps (AA 301-400) (AbBy Fluor® 750)
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- Antigène Voir toutes CDH18 Anticorps
- CDH18 (Cadherin 18, Type 2 (CDH18))
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Épitope
- AA 301-400
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDH18 est conjugé à/à la AbBy Fluor® 750
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Application
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CDH18
- Isotype
- IgG
- Top Product
- Discover our top product CDH18 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CDH18 (Cadherin 18, Type 2 (CDH18))
- Autre désignation
- CDH18 (CDH18 Produits)
- Synonymes
- anticorps B230220E17Rik, anticorps Cdh14l, anticorps CDH14, anticorps CDH14L, anticorps CDH24, anticorps cadherin 18, anticorps Cdh18, anticorps CDH18
- Sujet
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Synonyms: CAD18_HUMAN, Cadherin 14, Cadherin14, Cadherin 18, Cadherin18, Cadherin 18, type 2, Cadherin-14, Cadherin-18, CDH14, CDH14L, CDH18, CDH24, EY CADHERIN.
Background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis. EY-cadherin, also known as CDH18 (cadherin 18), CDH14 (cadherin 14), CDH24 or CDH14L, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains. One of several members of the cadherin superfamily, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), where it plays a role in cell-cell binding events. Specifically, EY-cadherin is thought to be involved in axon guidance and outgrowth, as well as synaptic adhesion within the CNS. EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, but lacks the HAV cell adhesion sequence that is specific to type I cadherins. The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, implicating EY-cadherin as a potential tumor suppressor.
- Pathways
- Cell-Cell Junction Organization
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