IL21 Receptor anticorps (Extracellular Domain)

N° du produit ABIN499988

Détail du produit anti-IL21 Receptor anticorps

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Épitope: Extracellular Domain

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL21 Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human IL-21 Receptor (Extracellular Domain) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 60 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur IL21 Receptor

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Autre désignation: Interleukin-21 Receptor / IL21R (IL21R Produits)

Synonymes: anticorps IL21R, anticorps il-21ra.a, anticorps CD360, anticorps NILR, anticorps interleukin 21 receptor, anticorps interleukin 21 receptor, tandem duplicate 1, anticorps IL21R, anticorps il21r.1, anticorps Il21r

Sujet: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21 . The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21R, IL21 receptor, NILR, Novel interleukin receptor

ID gène: 50615

NCBI Accession: NP_068570

UniProt: Q9HBE5

Pathways: Signalistation JAK/STAT