IL27 anticorps (N-Term)

N° du produit ABIN500000

Détail du produit anti-IL27 anticorps

Antigène: IL27 (Interleukin-27 Subunit alpha (IL27))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL27 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Specificité: This antibody reacts to IL-27.

Purification: Affinity chromatography purified via peptide column

Immunogène: Affinity chromatography purified via peptide column

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur IL27

Antigène: IL27 (Interleukin-27 Subunit alpha (IL27))

Autre désignation: Interleukin-27 / IL27A (IL27 Produits)

Synonymes: anticorps IL-27, anticorps IL-27A, anticorps IL27A, anticorps IL27p28, anticorps IL30, anticorps p28, anticorps EUROIMAGE1875335, anticorps IL25, anticorps IL27, anticorps IL27w, anticorps R33729_1, anticorps SF20, anticorps IL-27p28, anticorps Il30, anticorps interleukin 27, anticorps myeloid derived growth factor, anticorps IL27, anticorps MYDGF, anticorps Il27

Sujet: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28

ID gène: 246778

NCBI Accession: NP_663634

UniProt: Q8NEV9