STRADB anticorps (C-Term)

N° du produit ABIN500024

Détail du produit anti-STRADB anticorps

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: ILPIP antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human ILPIP.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human ILPIP (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 to 2 μg/mL. Aa 34 kDa band can be detected. Anti-ILPIP is specific forhuman ILPIP only. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur STRADB

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Autre désignation: STRAD beta / ILPIP (STRADB Produits)

Sujet: ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family (1). Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis (1,2). This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival (3), suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.Synonyms: ALS2CR2, CALS-21, PRO1038, Pseudokinase ALS2CR2, STE20-related kinase adapter protein beta, STRADB

ID gène: 55437

NCBI Accession: NP_061041

UniProt: Q9C0K7

Pathways: AMPK Signaling