CPA3 anticorps (AA 101-200) (AbBy Fluor® 750)
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- Antigène Voir toutes CPA3 Anticorps
- CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))
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Épitope
- AA 101-200
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CPA3 est conjugé à/à la AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CPA3/MC-CPA
- Isotype
- IgG
- Top Product
- Discover our top product CPA3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))
- Autre désignation
- CPA3/MC-CPA (CPA3 Produits)
- Synonymes
- anticorps MC-CPA, anticorps CPA3, anticorps mMC-CPA, anticorps carboxypeptidase A3, anticorps carboxypeptidase A4, anticorps carboxypeptidase A3, mast cell, anticorps CPA3, anticorps CPA4, anticorps Cpa3
- Sujet
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Synonyms: carboxypeptidase A, Carboxypeptidase A3, carboxypeptidase A3 mast cell, CBPA3_HUMAN, Cpa3, Mast cell carboxypeptidase A, mast cell carboxypeptidase A3, MC CPA, MC-CPA.
Background: Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
- ID gène
- 1359
- Pathways
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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