CTNND2 anticorps (AA 951-1050) (AbBy Fluor® 750)
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- Antigène Voir toutes CTNND2 Anticorps
- CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
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Épitope
- AA 951-1050
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CTNND2 est conjugé à/à la AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human delta 2 Catenin
- Isotype
- IgG
- Top Product
- Discover our top product CTNND2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
- Autre désignation
- CTNND2/delta 2 Catenin (CTNND2 Produits)
- Synonymes
- anticorps CTNND2, anticorps Catnd2, anticorps Nprap, anticorps neurojugin, anticorps GT24, anticorps NPRAP, anticorps ctnnd2, anticorps si:dkey-40c17.4, anticorps catenin delta 2, anticorps delta-catenin, anticorps catenin delta-2, anticorps catenin (cadherin associated protein), delta 2, anticorps catenin (cadherin-associated protein), delta 2b, anticorps CTNND2, anticorps BACOIKO001_27, anticorps LOC100070792, anticorps Ctnnd2, anticorps ctnnd2b
- Sujet
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Synonyms: Catenin cadherin associated protein delta 2, Catenin delta 2, Catenin delta-2, CTND2_HUMAN, CTNND 2, CTNND2, Delta catenin, Delta-catenin, GT 24, GT24, Neural plakophilin related arm repeat protein, Neural plakophilin related armadillo repeat protein, Neural plakophilin-related ARM-repeat protein, Neurojungin, NPRAP
Background: The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
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