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KDM3B anticorps (Center)

KDM3B Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500076
  • Antigène Voir toutes KDM3B Anticorps
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Épitope
    • 15
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 59
    • 35
    • 22
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 60
    • 1
    Lapin
    Clonalité
    • 61
    Polyclonal
    Conjugué
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KDM3B est non-conjugé
    Application
    • 47
    • 22
    • 13
    • 13
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects JMJD1B. It will not cross-react with JMJD1A or JMJD1C.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    JMJD1B antibody was raised against a 20 amino acid peptide from near the center of human JMJD1B.
    Isotype
    IgG
    Top Product
    Discover our top product KDM3B Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Autre désignation
    JMJD1B / KDM3B (KDM3B Produits)
    Synonymes
    anticorps KDM3B, anticorps JMJD1B, anticorps 5830462I21Rik, anticorps JHDM2B, anticorps Jmjd1b, anticorps mKIAA1082, anticorps 5qNCA, anticorps C5orf7, anticorps NET22, anticorps lysine demethylase 3B, anticorps lysine (K)-specific demethylase 3B, anticorps lysine-specific demethylase 3B, anticorps KDM3B lysine (K)-specific demethylase 3B, anticorps KDM3B, anticorps LOC100540242, anticorps kdm3b, anticorps Kdm3b
    Sujet
    The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA
    ID gène
    51780
    NCBI Accession
    NP_057688
    UniProt
    Q7LBC6
    Pathways
    L'effet Warburg
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