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Junctophilin 1 anticorps (C-Term)

JPH1 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500094
  • Antigène Voir toutes Junctophilin 1 (JPH1) Anticorps
    Junctophilin 1 (JPH1)
    Épitope
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    Humain, Souris, Rat
    Hôte
    • 12
    • 3
    Lapin
    Clonalité
    • 13
    • 2
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    Cet anticorp Junctophilin 1 est non-conjugé
    Application
    • 10
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects JPH1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    JPH1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human JPH1.
    Isotype
    IgG
    Top Product
    Discover our top product JPH1 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Junctophilin 1 (JPH1)
    Abstract
    JPH1 Produits
    Synonymes
    anticorps JP-1, anticorps JP1, anticorps ENSMUSG00000054314, anticorps Jp1, anticorps bZ1M12.3, anticorps jph1, anticorps si:rp71-1m12.3, anticorps Jph1, anticorps junctophilin 1, anticorps junctophilin 1a, anticorps junctophilin-1, anticorps JPH1, anticorps Jph1, anticorps jph1, anticorps jph1a, anticorps LOC100547979
    Sujet
    Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH1 is essential for stabilizing the T-tubule and SR membranes to form junctions and provide an environment for the assembly of receptors such as the ryanodine receptor type 1 (RyR1).Synonyms: JP1
    ID gène
    56704
    NCBI Accession
    NP_065698
    UniProt
    Q9HDC5
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