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NKIRAS1 anticorps (Center)

NKIRAS1 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500110
  • Antigène Voir toutes NKIRAS1 Anticorps
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 42
    • 31
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 50
    • 7
    Lapin
    Clonalité
    • 50
    • 7
    Polyclonal
    Conjugué
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NKIRAS1 est non-conjugé
    Application
    • 47
    • 27
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects both kappaB-ras1 and kappaB-ras2.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide afinity chromatography
    Immunogène
    KappaB ras antibody was raised against a 18 amino acid peptide from near the center of human KappaB ras 1.
    Isotype
    IgG
    Top Product
    Discover our top product NKIRAS1 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Autre désignation
    NKIRAS1 (NKIRAS1 Produits)
    Synonymes
    anticorps NKIRAS1, anticorps KBRAS1, anticorps kappaB-Ras1, anticorps zgc:92823, anticorps kbras1, anticorps 2400004O09Rik, anticorps NFKB inhibitor interacting Ras like 1, anticorps NFKB inhibitor interacting Ras-like 1, anticorps NFKB inhibitor interacting Ras-like 1 S homeolog, anticorps NFKB inhibitor interacting Ras-like protein 1, anticorps NKIRAS1, anticorps nkiras1, anticorps nkiras1.S, anticorps Nkiras1
    Sujet
    KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1
    ID gène
    28512
    UniProt
    Q9NYS0
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