KLHL1 anticorps (N-Term)

N° du produit ABIN500126

Détail du produit anti-KLHL1 anticorps

Antigène: KLHL1 (Kelch-Like 1 (KLHL1))

Épitope: N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Kelch-like 1 protein.

Réactivité croisée (Details): Species reactivity (tested):Human, rat

Purification: Peptide affinity chromatography

Immunogène: KLHL1 antibody was raised against a 14 amino acid peptide from near the amino-terminus of human KLHL1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 2 - 4 μg/mL. Human brain cell lysate can be used as positive control. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur KLHL1

Antigène: KLHL1 (Kelch-Like 1 (KLHL1))

Abstract: KLHL1 Produits

Synonymes: anticorps mKIAA1490, anticorps MRP2, anticorps kelch like family member 1, anticorps kelch-like 1, anticorps kelch-like family member 1, anticorps KLHL1, anticorps Klhl1

Sujet: The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues (1,2). The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins (3). Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression (1).Synonyms: KIAA1490, KLHL1

ID gène: 57626

UniProt: Q9NR64