LRRC1 anticorps (C-Term)

N° du produit ABIN500136

Détail du produit anti-LRRC1 anticorps

Antigène: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects LRRC1.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 -2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur LRRC1

Antigène: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Autre désignation: LRRC1 (LRRC1 Produits)

Synonymes: anticorps LRRC1, anticorps LANO, anticorps dJ523E19.1, anticorps A430093J20Rik, anticorps AU016091, anticorps D030059I21, anticorps mKIAA4018, anticorps leucine rich repeat containing 1, anticorps Lrrc1, anticorps LRRC1

Sujet: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble (1). The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells (2). Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions (1,3). It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues (4,5).Synonyms: LANO, LANO adapter protein, LAP and no PDZ protein, LRRC1, Leucine-rich repeat-containing protein 1

ID gène: 55227

UniProt: Q9BTT6