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LASS5 anticorps (N-Term)

LASS5 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500140
  • Antigène Voir toutes LASS5 Anticorps
    LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 21
    • 20
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 34
    • 1
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LASS5 est non-conjugé
    Application
    • 24
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects LASS5 at N-term. It may cross-react with the highly homologous LASS6.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    LASS5 antibody was raised against a 18 amino acid peptide near the amino terminus of the human LASS5.
    Isotype
    IgG
    Top Product
    Discover our top product LASS5 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))
    Autre désignation
    LASS5 (LASS5 Produits)
    Synonymes
    anticorps lass5, anticorps trh4, anticorps LASS5, anticorps Trh4, anticorps 2310081H14Rik, anticorps AU045339, anticorps AW544927, anticorps Lass5, anticorps ceramide synthase 5, anticorps ceramide synthase 5 S homeolog, anticorps CERS5, anticorps cers5, anticorps cers5.S, anticorps Cers5
    Sujet
    The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis. Multiple isoforms of LASS5 are known to exist.Synonyms: LAG1 longevity assurance homolog 5, LASS5, TRAM homolog 4, TRH4, Translocating chain-associating membrane protein homolog 4
    ID gène
    91012
    NCBI Accession
    NP_671723
    UniProt
    Q8N5B7
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