DOCK4 anticorps (AA 1001-1100) (AbBy Fluor® 680)
-
- Antigène Voir toutes DOCK4 Anticorps
- DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
-
Épitope
- AA 1001-1100
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DOCK4 est conjugé à/à la AbBy Fluor® 680
-
Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DOCK4
- Isotype
- IgG
- Top Product
- Discover our top product DOCK4 Anticorps primaire
-
-
- Indications d'application
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
- Autre désignation
- DOCK4 (DOCK4 Produits)
- Synonymes
- anticorps DOCK4, anticorps 5330406C03, anticorps 6330411N01Rik, anticorps AF263288, anticorps C030023J22, anticorps mKIAA0716, anticorps dedicator of cytokinesis 4, anticorps DOCK4, anticorps NAEGRDRAFT_81257, anticorps Dock4
- Sujet
-
Synonyms: Dedicator of cytokinesis protein 4, Dock4, DOCK4_HUMAN, KIAA0716.
Background: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.
- ID gène
- 9732
-