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FBXO21 anticorps (AbBy Fluor® 750)

FBXO21 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 750
N° du produit ABIN5002524
  • Antigène Voir toutes FBXO21 Anticorps
    FBXO21 (F-Box Protein 21 (FBXO21))
    Reactivité
    • 39
    • 38
    • 24
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 38
    • 8
    Lapin
    Clonalité
    • 40
    • 6
    Polyclonal
    Conjugué
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FBXO21 est conjugé à/à la AbBy Fluor® 750
    Application
    • 46
    • 22
    • 13
    • 12
    • 10
    • 7
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FBXO21
    Isotype
    IgG
    Top Product
    Discover our top product FBXO21 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FBXO21 (F-Box Protein 21 (FBXO21))
    Autre désignation
    FBXO21 (FBXO21 Produits)
    Synonymes
    anticorps FBX21, anticorps 2810425J22Rik, anticorps AU016673, anticorps mKIAA0875, anticorps si:ch211-42a13.2, anticorps F-box protein 21, anticorps FBXO21, anticorps Fbxo21, anticorps fbxo21
    Sujet

    Synonyms: F box only protein 21, F box protein 21, F-box only protein 21, FBX21, FBX21_HUMAN, Fbxo21, FLJ90233, KIAA0875, MGC26682.

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.

    ID gène
    23014
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