LY86 anticorps (Center)

N° du produit ABIN500260

Détail du produit anti-LY86 anticorps

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LY86 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects MD-1 at center.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: MD-1 antibody was raised against a 15 amino acid peptide from near the center of human MD-1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur LY86

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Autre désignation: LY86 / MD-1 (LY86 Produits)

Synonymes: anticorps MD-1, anticorps MMD-1, anticorps dJ80N2.1, anticorps MD1, anticorps LY86, anticorps lymphocyte antigen 86, anticorps LY86, anticorps Ly86

Sujet: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1

ID gène: 9450

NCBI Accession: NP_004262

UniProt: O95711

Pathways: Toll-Like Receptors Cascades