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LY86 anticorps (Center)

LY86 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500260
  • Antigène Voir toutes LY86 Anticorps
    LY86 (Lymphocyte Antigen 86 (LY86))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 43
    • 9
    • 4
    Lapin
    Clonalité
    • 45
    • 11
    Polyclonal
    Conjugué
    • 22
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LY86 est non-conjugé
    Application
    • 41
    • 19
    • 13
    • 13
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects MD-1 at center.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    MD-1 antibody was raised against a 15 amino acid peptide from near the center of human MD-1.
    Isotype
    IgG
    Top Product
    Discover our top product LY86 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    LY86 (Lymphocyte Antigen 86 (LY86))
    Autre désignation
    LY86 / MD-1 (LY86 Produits)
    Synonymes
    anticorps MD-1, anticorps MMD-1, anticorps dJ80N2.1, anticorps MD1, anticorps LY86, anticorps lymphocyte antigen 86, anticorps LY86, anticorps Ly86
    Sujet
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1
    ID gène
    9450
    NCBI Accession
    NP_004262
    UniProt
    O95711
    Pathways
    Toll-Like Receptors Cascades
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